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VOLUME 1 , ISSUE 2 ( April-June, 2022 ) > List of Articles


Neonatal Acute Liver Failure

Gurpreet Kaur Grewal, Horacio Osiovich, Richard Schreiber

Keywords : Diagnosis, Enterovirus, Gestational alloimmune liver disease, Hemophagocytic lymphohistocytosis, Neonatal acute liver failure, Neonatal disease, Neonate

Citation Information : Grewal GK, Osiovich H, Schreiber R. Neonatal Acute Liver Failure. 2022; 1 (2):254-262.

DOI: 10.5005/jp-journals-11002-0029

License: CC BY-NC 4.0

Published Online: 05-07-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Acute liver failure is a rare event in the newborn period yet early recognition in the neonatal intensive care setting is essential for best outcome. Neonatal acute liver failure (NALF) is distinct from acute liver failure in older children and adults having different etiologies, presentation, and unique treatment interventions. There is a paucity of literature regarding NALF and several newly identified conditions merit discussion. Herein we report three cases of liver failure who were admitted to our neonatal intensive care unit and review the diagnostic approach and management of liver failure in this age group.

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